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Three-dimensional reconstruction of Echinococcus multilocularis larval growth in human hepatic tissue reveals complex growth patterns

 
: Tappe, D.; Zidowitz, S.; Demmer, P.; Kern, P.; Barth, T.F.E.; Frosch, M.

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American journal of tropical medicine and hygiene 82 (2010), Nr.1, S.126-127
ISSN: 0002-9637
Englisch
Zeitschriftenaufsatz
Fraunhofer MEVIS ()

Abstract
In this study we present, for the first time, a three-dimensional digital reconstruction of Echinococcus multilocularis larval growth in human tissue. Formalin-fixed, paraffin-embedded hepatic tissues from patients with alveolarechinococcosis were serially sectioned, stained, and areas of larval growth of the parasite were microphotographed. Parasitic structures were reconstructed from multiple digital planes, revealing a root-like network of interconnected vesiclesand tubules extending into the periphery of lesions.

: http://publica.fraunhofer.de/dokumente/N-117788.html