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2009
Journal Article
Titel
Antibacterial and abrasion-resistant alumina micropatterns
Abstract
In summary, we demonstrate that it is feasible to fabricate surfaces that feature antibacterial and abrasion-resistance properties at the same time by combining micropatterning with antibacterial enzymes and alumina nanoparticles. In particular, we have shown that antibacterial activity of lysozyme is maintained when the enzyme is adsorbed on alumina surfaces and that it can be efficiently protected by surface micropatterning even at abrasive and harsh chemical conditions. Therefore, antibacterial features may potentially be maintained over a long-time period. Furthermore, we show that natural antimicrobial enzymes, such as lysozyme, can be successfully employed to protect surfaces from bacterial colonization. Antimicrobial enzymes may present a valid alternative to the most commonly used but non-effective biocides in biofouling prevention.