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Differential expression of myogenic determination genes in musle cells - possible autoactivation by the Myf gene products

: Arnold, H.-H.; Bober, E.; Braun, T.; Buschhausen-Denker, G.; Grzeschik, K.-H.; Kotz, S.

EMBO Journal 8 (1989), No.12, pp.3617-3625
ISSN: 0261-4189
Journal Article
Fraunhofer ITA ( ITEM) ()
amino acid sequence; autoregulation; base sequence; cell determination; cell line; chromosome mapping; gene; gene expression regulation; genetic; human myogenic factor; molecular sequence data; muscle protein; regulatory network

The development of muscle cells involves the action of myogenic determination factors. In this report, we show that human skeletal muscle tissue contains, beside the previously described Myf-5, two additional factors Myf-3 and Myf-4 which represent the human homologues of the prodent roteins MyoD1 and myogenin.