Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.

Vorrichtung und Verfahren zur Produktion von Singulett-Sauerstoff

Apparatus to generate local singlet oxygen for cancer therapy.
 
: Koehl, M.; Brucker, F.; Lieske, V.

:
Frontpage ()

DE 1998-19835456 A: 19980805
DE 1998-19835456 A: 19980805
WO 1999-EP5667 A: 19990805
EP 1999-940153 A: 19990805
DE 19835456 C1: 19991028
EP 1100748 B1: 20030416
B01J0019
C01B0013
German
Patent, Electronic Publication
Fraunhofer ISE ()

Abstract
Es wird eine Vorrichtung zum Erzeugen von Singulett-Sauerstoff mit einer Lichtquelle (1) und einem transparenten Medium (2) beschrieben. Das transparente Medium (2) weist eine erste und eine zweite Oberflaeche auf, wobei die erste Oberflaeche der Lichtquelle (1) zugewandt ist und auf der zweiten Oberflaeche ein Bereich (3) angeordnet ist, der einen Photosensibilisator enthaelt.

 

DE 19835456 C UPAB: 19991201 NOVELTY - Apparatus (I) for the production of singlet oxygen from triplet oxygen, has a light source (1) and a transparent medium (2) with two surfaces. The light (1) can be coupled in the transparent medium through the first surface. The second surface has a zone (3) which contains at least one photosensitizer. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is also included for a process (II) where singlet oxygen is produced from triplet oxygen by the use of light which is coupled to a transparent medium (2). The light is conducted within the transparent medium (2) to a surface which has a zone (3) containing at least one photosensitizer in contact with triplet oxygen. The triplet oxygen is subjected to a photo-induced excitation to be converted into singlet oxygen through the photosensitizer. MECHANISM OF ACTION - None given. USE - (I) together with a light conductor, is for the emission of oxygen and/or a gas with an oxygen content and/or a photosensitizer. It is used in cancer therapy. ADVANTAGE - The procedure has reduced side effects on the patient, the singlet oxygen is applied locally to the target areas, and the patient does not have to remain for long periods in a darkened environment for an injected photosensitizer to degrade.

: http://publica.fraunhofer.de/documents/PX-63424.html