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Atypical malignant mesotheliomas with osseous and cartilaginous differentiation after intraperitoneal injection of various types of mineral fibres in rats

: Ernst, H.; Mohr, U.; Muhle, H.; Rittinghausen, S.

	Experimental and Toxicologic Pathology 44 (1992), No.1, pp.55-58 : Abb.,Lit. ISSN: 0940-2993

	English
	Journal Article
	Fraunhofer ITA ( ITEM) ()
	abdominal cavity; asbestos; atypical malignant mesotheliomas; cartilaginous differentiation; mineral fibre; neoplasms; osseous differentiation; pathology; rat; toxicology; tumor

Abstract
The histopathological appearance of malignant mesotheliomas with osseous and cartilaginous differentiation is described in detail. Bone and cartilage occurred in mixed and sarcomatoid mesotheliomas which were induced by intraperitoneal injection of various types of asbestos fibres (asbestos cement, crocidolite, UICC-amosite, UICC- chrysotile B, Calidria-chrysotile). Bone or cartilage were found in 32.7% of mixed mesothelioma and in 12.8% of sarcomatoid mesotheliomas.

: http://publica.fraunhofer.de/documents/PX-4807.html