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The assessment of intramural stress alignment on the beating heart in situ using micro-ergometry

Functional implications
: Lunkenheimer, P.P.; Redmann, K.; Dietl, K.H.; Stroh, N.; Richter, K.D.; Niederer, P.; Cryer, C.

Technology and health care 5 (1997), No.1-2, pp.115-122
ISSN: 0928-7329
Journal Article
Fraunhofer IGB ()
animal disease model; exercise test; hypertrophy; microelectrodes; myocardium; ventricular function

The main local stress transmission pathways in the left ventricular base, midportion and apex in up to seven layers hae been assessed in normal dog and porcine hearts, in hypertrophied dog hearts, and in three pig hearts having undergone a temporary left ventricular outflow stricture. The rotational sensitivity of needle force probes was used to determine the focal surface-parallel direction of the myocardial tension vector. In all places investigated the orientation of the force transmission pathways differs slightly from the morphologically determined fibre alignment. Vector rotation upon an axis normal to the epicardial surface is definitely tempered as compared to fibre rotation. Alterations in the force transmission pathways assessed in hypertrophied dog hearts by micro-ergometry qualitatively confirm structural remodelling in so far as an irregularity in the transmural rotation of the main stress vector was found. The measured disparities between the alignment of the myocardial f ibre weave and the direction of stress transmission both in the normal and the diseased heart is widely individual, and hence, scattering of the data is marked. However, it must also be called into consideration that the measured orientation of force vectors is that at the moment of highest developed force, only. Further investigations will elucidate if discrepancies between that force vector and morphology are less pronounced when the vector is averaged over the entire heart cycle.