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  4. Ameloblastoma in a female Wistar rat
 
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1995
Journal Article
Title

Ameloblastoma in a female Wistar rat

Abstract
A spontaneous ameloblastoma of the right mandible is described in a 120-week-old female Wistar rat. The tumour had a locally aggressive growth pattern and was histologically characterized by sheets and islands of odontogenic epithelium bounded by a palisaded layer of ameloblast-like cells. Because of multifocal keratinizing squamous metaplasia of the stellate reticulum tissue, the tumour was classified as an acanthomatous ameloblastoma. Cyst formation, areas of stromal hyalinization and enamel matrix-like inclusions were further characteristics of the neoplasm. The epithelial elements stained strongly positive for broad spectrum cytokeratins.
Author(s)
Ernst, H.
Mirea, D.
Journal
Experimental and Toxicologic Pathology  
Language
English
ITA  
Keyword(s)
  • histology

  • mouth

  • rat

  • tumor

  • tumor pathology

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