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Aktivierung von Makrophagen durch Polysaccharide aus Gewebekulturen von Echinacea purpurea

Macrophage activation by plant polysaccharides
 
: Lohmann-Matthes, M.-L.; Wagner, H.

Zeitschrift für Phytotherapie 10 (1989), pp.52-59
ISSN: 0722-348X
German
Journal Article
Fraunhofer ITA ( ITEM) ()
Echinacea purpurea; Immunologie; immunology; in vivo; infection; Infektion; macrophage; macrophage activation; Makrophage; Makrophagenaktivierung; monokine; polysaccharid

Abstract
Polysaccharides from plant cell cultures of Echinacea purpurea have been found to be very effective in activating macrophages both in vitro and in vivo. Macrophages stimulated with these polysaccharides produce tumor necrosis factor alpha, interleukin 1 and interferon beta. They are also activated to cytotoxicity against tumor cells and microorganisms. Applied intravenously these polysaccharides protect mice very efficiently from lethal infections with Candida albicans or Listeria monocytogenes.

: http://publica.fraunhofer.de/documents/PX-3489.html