Simulation and optimization of biochemical production processes

A program for dynamic and steady state simulation of biochemical production processes is presented. For plant simulation the sequential modular approach, where each type of a module is simulated by a subroutine that solves for the outlet streams given the inlet streams and module parameters as input data has been adopted. So far subroutines for the simulation of various reactors and ultrafiltration modules have been developed. With these subroutines complex reaction systems including different enzyme catalyzed reactions can be simulated in various apparatus. To illustrate the types of calculations that can be performed, some simulation results which deal with the optimization of an enzymatic production process will be discussed.