• English
  • Deutsch
  • Log In
    Password Login
    Research Outputs
    Fundings & Projects
    Researchers
    Institutes
    Statistics
Repository logo
Fraunhofer-Gesellschaft
  1. Home
  2. Fraunhofer-Gesellschaft
  3. Konferenzschrift
  4. Histopathological analysis of tumour types after intraperitoneal injection of mineral fibers in rats
 
  • Details
  • Full
Options
1991
Conference Paper
Title

Histopathological analysis of tumour types after intraperitoneal injection of mineral fibers in rats

Abstract
Female rats were treated twice by an intraperitoneal injection of mineral fibres. The treatment led to malignant tumours in the peritoneal cavity. Most of these tumours were classified as malignant mesotheliomas. Some rats had undifferentiated sarcomas rather than mesotheliomas. Three different types of malignant mesotheliomas can be distinguished: epithelioid, sarcomatoid and mixed. Cartilaginous or osseous differentiation occuring in mesotheliomas has only been described as a biological feature in a few cases of mesotheliomas of the pleura in man (Goldstein, 1979; McCaughey, 1958; Yousem and Hochholzer, 1987). Some of the affected persons were known to have been exposed to asbestos (Goldstein, 1979; Yousem and Hochholzer, 1987). In the following report histopathological features of malignant mesotheliomas occurring in the abdominal cavity after intraperitoneal injection of different types of mineral fibres in female Wistar rats are described. Additionally, the number of animals with mesotheliomas, according to the injected fibre type is presented.
Author(s)
Rittinghausen, S.
Ernst, H.
Muhle, H.
Fuhst, R.
Mohr, U.
Mainwork
Mechanisms in fibre carcinogenesis  
Conference
Advanced Research Workshop on Mechanisms in Fibre Carcinogenesis 1990  
Language
English
ITA  
Keyword(s)
  • mesothelioma

  • Mineral fibers

  • pathological histology

  • rat

  • Tumor Classification

  • Tumors

  • Cookie settings
  • Imprint
  • Privacy policy
  • Api
  • Contact
© 2024