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Generation of exposure atmospheres

: Koch, W.

Jenkins, P.G.; Kayser, D.; Muhle, H.; Rosner, G.; Smith, E.M. ; Medizinische Hochschule Hannover; International Life Sciences Institute -ILSI-, Washington/D.C.; Bundesministerium für Umwelt, Naturschutz und Reaktorsicherheit -BMU-, Bonn; Fraunhofer-Institut für Toxikologie und Aerosolforschung -ITA-, Hannover:
Respiratory toxicology and risk assessment. Proceedings of an International Symposium
Stuttgart: Wissenschaftliche Verlags-Gesellschaft, 1994 (IPCS Joint Series 18)
ISBN: 3-8047-1327-0
International Symposium "Respiratory Toxicology and Risk Assessment" <1992, Hannover>
Conference Paper
Fraunhofer ITA ( ITEM) ()
chemistry; experiments; Exposition; gases; inhalation toxicology; medicine; particles; toxicity testing; toxicology

Introduction: Results of controlled inhalation studies should serve as a data base to assess the risk of human exposure to airborne substances that might have adverse health effects. The simulated exposure atmosphere should therefore match as closely as possible human exposure to the substance under consideration. The engineers contribution to a successful inhalation study is to provide a suitable technique for a controlled and reproducible generation of the exposure atmosphere. This requires a profound understanding of the underlying physical and chemical principles. (Truncated)