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Funnels in energy landscapes

: Klemm, K.; Flamm, C.; Stadler, P.F.


The European physical journal. B, Condensed matter physics 63 (2008), No.3, pp.387-391
ISSN: 1434-6028
Journal Article
Fraunhofer IZI ()

Local minima and the saddle points separating them in the energy landscape are known to dominate the dynamics of biopolymer folding. Here we introduce a notion of a "folding funnel" that is concisely defined in terms of energy minima and saddle points, while at the same time conforming to a notion of a "folding funnel" as it is discussed in the protein folding literature.