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2004
Conference Paper
Titel
Monitoring dielectrophoretic collection of DNA by impedance measurement
Abstract
Double stranded M13 phagemid DNA has been locally concentrated between interdigitated electrodes by dielectrophoresis. RF electric fields at 0.1 MHz and 1 MHz have been applied with field strengths exceeding 1 MV/m. Impedance changes were monitored by analysis of the driving signals or with an additional sensing signal applied at 1 kHz. DNA collection was found to be reflected clearly by changes in the capacitive part of the setup's impedance. This presents a new method for a label free, purely electronic detection of macromolecules.