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CREx: inferring genomic rearrangements based on common intervals



Bioinformatics 23 (2007), No.21, pp.2957-2958
ISSN: 1367-4803
ISSN: 1460-2059
Journal Article
Fraunhofer IZI ()

Summary: We present the web-based program CREx for heuristically determining pairwise rearrangement events in unichromosomal genomes. CREx considers transpositions, reverse transpositions, reversals and tandem-duplication-random-loss (TDRL) events. It supports the user in finding parsimonious rearrangement scenarios given a phylogenetic hypothesis. CREx is based on common intervals, which reflect genes that appear consecutively in several of the input gene orders.