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Evaluation of a dermal carcinogenicity study with mice with two different creosotes

Auswertung einer dermalen Kanzerogenitätsstudie an Mäusen mit zwei verschiedenen Teerölprodukten
: Mangelsdorf, I.; Boehncke, A.; Holländer, W.
: Fraunhofer-Institut für Toxikologie und Aerosolforschung -ITA-, Hannover

1998, 27 pp.
English, German
Fraunhofer ITA ( ITEM) ()
carcinogen; creosote; dermatology; mice

According to current legislation of the European Union, creosotes which contain benzo(a)pyrene (BaP) at a concentration of more than 50 ppm must be classified as carcinogenic. The sale of such creosotes for the treatment of wood to private consumers is forbidden. In contrast, under EU law, creosotes with a BaP content below 50 ppm are not subject to any restriction whatsoever. Based on the findings of a dermal carcinogenicity study with mice recently concluded at the Fraunhofer Institute for Toxicology and Aerosol Research (FH-ITA) in Hannover, it is our intention here (with this publication) to examine the evidence for a carcinogenic effect of creosotes with BaP content under 50 ppm....