• English
  • Deutsch
  • Log In
    Password Login
    Research Outputs
    Fundings & Projects
    Researchers
    Institutes
    Statistics
Repository logo
Fraunhofer-Gesellschaft
  1. Home
  2. Fraunhofer-Gesellschaft
  3. Artikel
  4. Accuracy of a magnetic resonance imaging-based 3D printed stereotactic brain biopsy device in dogs
 
  • Details
  • Full
Options
2020
Journal Article
Title

Accuracy of a magnetic resonance imaging-based 3D printed stereotactic brain biopsy device in dogs

Abstract
BACKGROUND: Brain biopsy of intracranial lesions is often necessary to determine specific therapy. The cost of the currently used stereotactic rigid frame and optical tracking systems for brain biopsy in dogs is often prohibitive or accuracy is not sufficient for all types of lesion. OBJECTIVES: To evaluate the application accuracy of an inexpensive magnetic resonance imaging-based personalized, 3D printed brain biopsy device. ANIMALS: Twenty-two dog heads from cadavers were separated into 2 groups according to body weight (<15 kg, >20 kg).METHODS: Experimental study. Two target points in each cadaver head were used (target point 1: caudate nucleus, target point 2: piriform lobe). Comparison between groups was performed using the independent Student's t test or the nonparametric Mann-Whitney U Test. RESULTS: The total median target point deviation was 0.83 mm (range 0.09-2.76 mm). The separate median target point deviations for target points 1 and 2 in all dogs were 0.57 mm (range: 0.09-1.25 mm) and 0.85 mm (range: 0.14-2.76 mm), respectively. CONCLUSION AND CLINICAL IMPORTANCE: This magnetic resonance imaging-based 3D printed stereotactic brain biopsy device achieved an application accuracy that was better than the accuracy of most brain biopsy systems that are currently used in veterinary medicine. The device can be applied to every size and shape of skull and allows precise positioning of brain biopsy needles in dogs.
Author(s)
Gutmann, Sarah
Universität Leipzig
Winkler, Dirk
Universitätsklinikum Leipzig
Müller, Marcel  
Fraunhofer-Institut für Werkzeugmaschinen und Umformtechnik IWU  
Möbius, Robert
Universitätsklinikum Leipzig
Fischer, Jean-Pierre
Universitätsklinikum Leipzig
Böttcher, P.
Kiefer, Ingmar
Universität Leipzig
Grunert, Ronny  
Fraunhofer-Institut für Werkzeugmaschinen und Umformtechnik IWU  
Flegel, Thomas
FU Berlin
Journal
Journal of veterinary internal medicine : JVIM  
Open Access
DOI
10.1111/jvim.15739
Additional full text version
Landing Page
Language
English
Fraunhofer-Institut für Werkzeugmaschinen und Umformtechnik IWU  
Keyword(s)
  • 3D printing

  • MRI

  • brain biopsy

  • canine

  • neurosurgery

  • personalized

  • Cookie settings
  • Imprint
  • Privacy policy
  • Api
  • Contact
© 2024