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Urethanes PDMS-based: Functional hybrid coatings for metallic dental implants

 
: Rossi De Aguiar, Kelen M.F.; Nascimento, Matheus V.; Faccioni, Juliano L.; Noeske, Michael; Gätjen, Linda; Rischka, Klaus; Rodrigues-Filho, Ubirajara P.

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Applied surface science (2019), 484, pp.1128-1140
ISSN: 0169-4332
English
Journal Article
Fraunhofer IFAM ()
Urethanes; PDMS-based; hybrid coatings

Abstract
In this study, we propose new polymeric coatings for metallic implants that impart biocompatibility and antibacterialfeatures to such surfaces. The starting material, poly(cyclic carbonate)-polydimethylsiloxane, wasprepared from carbon dioxide fixation and then sequentially reacted by aminolysis with an organoaminosilane,affording the formation of an urethanic polydimethylsiloxane-based material. Finally, a hybrid coating wasobtained by performing a sol-gel process on the metallic surfaces, catalyzed by phosphotungstic acid. We provideevidence that due to the polydimethylsiloxane segments governing the surface termination, the hybrid coatingsshow a hydrophobic character. Furthermore, due the presence of phosphotungstic acid in the upper surface, theadhesion of Gram-positive and Gram-negative bacteria is suppressed in 4 h of contact with aqueous bacterialcultures. In addition, the coatings presented a>70% cytocompatibility besides a low cytotoxicity, making theminteresting candidates as biocompatible materials and an alternative to avoiding the biofilm associated withbacterial infections.

: http://publica.fraunhofer.de/documents/N-552026.html