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Dengue Virus IgM Serotyping by ELISA with Recombinant Mutant Envelope Proteins

 
: Rockstroh, Alexandra; Barzon, Luisa; Kumbukgolla, Widuranga; Su, Hoang Xuan; Lizarzo, Erley; Vincenti-Gonzalez, Maria Fernanda; Tami, Adriana; Ornelas, Alice M.M.; Aguiar, Renato Santana; Cadar, Daniel; Schmidt-Chanasit, Jonas; Ulbert, Sebastian

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Fulltext ()

Emerging infectious diseases 25 (2019), No.1, pp.112-115
ISSN: 1080-6040
ISSN: 1080-6059
English
Journal Article, Electronic Publication
Fraunhofer IZI ()
Denguefieber; ELISA for IgM; Viruses; cross-reactivity; virus disease

Abstract
We developed an IgM-based ELISA that identifies the dengue virus serotype of recent infections. Dominant serotypes were detectable in 91.1% of samples from travelers and 86.5% of samples from residents of endemic regions; 97.1% corresponded to the serotype identified by PCR. This ELISA enables more accurate reporting of epidemiologic findings.

: http://publica.fraunhofer.de/documents/N-549550.html