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Differential Shedding and Antibody Kinetics of Zika and Chikungunya Viruses, Brazil

 
: Bozza, Fernando A.; Moreira-Soto, Andres; Rockstroh, Alexandra; Fischer, Carlo; Nascimento, Alessandra D.; Calheiros, Andrea S.; Drosten, Christian; Bozza, Patrícia T.; Souza, Thiago Moreno L.; Ulbert, Sebastian; Drexler, Jan Felix

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Emerging infectious diseases 25 (2019), No.2, pp.311-315
ISSN: 1080-6040
ISSN: 1080-6059
European Commission EC
H2020; 734548; ZIKAlliance
A global alliance for Zika virus control and prevention
English
Journal Article, Electronic Publication
Fraunhofer IZI ()
Zika virus; Chikungunya virus; Viruses; virus disease

Abstract
In seroconversion panels obtained from patients from Brazil, diagnostic testing for Zika virus infection was improved by combining multiple antibody isotypes, techniques, and antigens, but sensitivity remained suboptimal. In contrast, chikungunya virus diagnostic testing was unambiguous. Recurrent recent arbovirus infections suggested by serologic data and unspecific symptoms highlight the need for exhaustive virologic testing.

: http://publica.fraunhofer.de/documents/N-549459.html