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Draft genomes and reference transcriptomes extend the coding potential of the fish pathogen Piscirickettsia salmonis

 
: Millar, A.D.; Tapia, P.; Gomez, F.A.; Marshall, S.H.; Fuentes, D.E.; Valdes, J.H.

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Fulltext ()

Electronic journal of biotechnology : EJB 33 (2018), pp.36-38
ISSN: 0717-3458
English
Journal Article, Electronic Publication
Fraunhofer Chile Research - Centro para la Biotecnología de Sistemas ()

Abstract
Background: Draft and complete genome sequences from bacteria are key tools to understand genetic determinants involved in pathogenesis in several disease models. Piscirickettsia salmonis is a Gram-negative bacterium responsible for the Salmon Rickettsial Syndrome (SRS), a bacterial disease that threatens the sustainability of the Chilean salmon industry. In previous reports, complete and draft genome sequences have been generated and annotated. However, the lack of transcriptome data underestimates the genetic potential, does not provide information about transcriptional units and contributes to disseminate annotation errors.
Results: Here we present the draft genome and transcriptome sequences of four P. salmonis strains. We have identified the transcriptional architecture of previously characterized virulence factors and trait-specific genes associated to cation uptake, metal efflux, antibiotic resistance, secretion systems and other virulence factors.
Conclusions: This data has provided a refined genome annotation and also new insights on the transcriptional structures and coding potential of this fish pathogen. Millar AD, Tapia P, Gomez FA, et al. Draft genomes and reference transcriptomes extend the coding potential of the fish pathogen Piscirickettsia salmonis. Electron J Biotechnol 2018;33. https://doi.org/10.1016/j.ejbt.2018.04.002.

: http://publica.fraunhofer.de/documents/N-524689.html