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Lab-on-a-chip device for rapid measurement of vitamin D levels

: Peter, H.; Bistolas, N.; Schumacher, S.; Laurisch, C.; Guest, P.C.; Höller, U.; Bier, F.F.


Guest, P.C.:
Investigations of early nutrition effects on long-term health. Methods and applications
New York: Humana Press, 2018 (Methods in molecular biology 1735)
ISBN: 978-1-4939-7613-3 (Print)
ISBN: 978-1-4939-7614-0 (Online)
ISBN: 1-4939-7613-3
Book Article
Fraunhofer IZI ()

Lab-on-a-chip assays allow rapid analysis of one or more molecular analytes on an automated user-friendly platform. Here we describe a fully automated assay and readout for measurement of vitamin D levels in less than 15 min using the Fraunhofer in vitro diagnostics platform. Vitamin D (25-hydroxyvitamin D3 [25(OH)D3]) dilution series in buffer were successfully tested down to 2 ng/mL. This could be applied in the future as an inexpensive point-of-care analysis for patients suffering from a variety of conditions marked by vitamin D deficiencies.