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Electrophysiological Characterization of Neurotropic Activity of Sideritis Tea Volatiles

 
: Kessler, A.; Villmann, C.; Sahin, H.; Pischetsrieder, M.; Büttner, A.

:

Ferreira, V. (Ed.):
Flavour Science. XIII Weurman Flavour Research Symposium 2011. Proceedings : Zaragoza in September 2011
Amsterdam: Elsevier Academic Press, 2014
ISBN: 978-0-12-398549-1
ISBN: 0-12-398549-8
ISBN: 978-0-12-401724-5 (eBook)
pp.71-75
Weurman Flavour Research Symposium <13, 2011, Zaragoza>
English
Conference Paper
Fraunhofer IVV ()

Abstract
Sideritis spp. is a member of the Labiateae plant family, and used for tea infusions with claimed sedative properties. To clarify if the volatile fractions of the plant material can exert a sedative effect via γ-aminobutyric acid (GABA) signaling, a dichloromethane (DCM) aroma extract of the aerial parts was prepared. The volatile fraction was separated via solvent assisted flavor evaporation (SAFE) distillation. In electrophysiological recordings using the two-electrode voltage clamp technique (TEVC), the plant extract of Sideritis species showed potentiation effects of the maximal GABA-induced response on GABAA receptors comparable to those of lavender.

: http://publica.fraunhofer.de/documents/N-473281.html