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  4. Measurements of dermal uptake of nicotine directly from air and clothing
 
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2017
Conference Paper
Title

Measurements of dermal uptake of nicotine directly from air and clothing

Abstract
Dermal uptake directly from air is a significant contributor to total exposure for certain organic compounds, and has been recently experimentally verified for two phthalates. The objective of the current study was to investigate whether airborne nicotine can be dermally absorbed. Two bare-skinned subjects together with a subject wearing clean clothes were dermally exposed to environmental tobacco smoke (ETS) for three hours in a climate chamber; during the exposure all three subjects breathed clean air through hoods covering their heads. The clothed subject later repeated his exposure wearing a shirt previously exposed to tobacco smoke. Urine samples were subsequently analyzed for nicotine and two of its metabolites. The results demonstrate that nicotine can be dermally absorbed directly from air atrates comparable to passive smoking. Wearing clean clothes significantly decreases uptake, while wearing exposed clothes results in substantial uptake.
Author(s)
Bekö, G.
Morrison, G.
Weschler, C.J.
Koch, H.M.
Salthammer, T.
Schripp, T.
Toftum, J.
Clausen, G.
Mainwork
14th International Conference on Indoor Air Quality and Climate, Indoor Air 2016. Vol.4  
Conference
International Conference on Indoor Air Quality and Climate (Indoor Air) 2016  
Language
English
Fraunhofer-Institut für Holzforschung Wilhelm-Klauditz-Institut WKI  
Keyword(s)
  • exposure pathway

  • biomonitoring

  • indoor environment

  • e-cigarettes

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