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Dreidimensionale nano- und mikrostrukturierte Traeger

Three-dimensional nano and micro structured supports, for identifying DNA molecule, comprises a metal, metallic oxide, hydraulic gel, semiconductor material, glass, ceramic and a protein-stabilizing agent, which is on connecting device.
: Tovar, G.; Weber, A.; Brunner, H.; Borchers, K.

Frontpage ()

DE 102004062573 A: 20041224
DE 2004-102004062573 A: 20041224
DE 102004062573 A1: 20060713
Patent, Electronic Publication
Fraunhofer IGB ()

Die vorliegende Erfindung betrifft Funktionselemente, die auf einem Traeger angeordnete, biofunktionalisierte Nanopartikel enthaltende Mikrostrukturen umfassen, Verfahren zur Herstellung dieser Funktionselemente sowie die Verwendung derselben.


WO2006072306 A UPAB: 20060822 NOVELTY - The device is adjusted by changing pH value/concentration/temperature. The antibodies, antigen, enzymes cytokine, receptors, nucleic acid and/or DNA molecules are bounded covalently or non-covalently. Functional groups are produced by molecular coining/shaping and spacer with organic/inorganic materials connects the groups. The core has a size of 5-500 nm and has function of a fluorescence marking, UV/marking, super paramagnetic, ferrous magnetic and/or a radioactive marking function. DETAILED DESCRIPTION - The supports has thickness of 100 nm-1.5 mu m. The organic materials are polypropylene, polystyrene, and/or polyacrylate. The inorganic material is Ag or Ni, silicon, SiO2, SiO, a silicate, Al2O3, SiO2Al2O3, Fe2O3, Ag2O, TiO2, ZrO2, Zr2O3, Ta2O5, zeolite, glass, indium tin oxide and/or hydroxyl apatite. INDEPENDENT CLAIMS are also included for: (1) the preparation of the nano and micro structured supports; and (2) a method for the identification/analysis of a solution. USE - Used for identification of biological molecules such as DNA molecule. Used for the detection fluorescence, UV, spectroscopy, light microscopy or transverse electromagnetic wave spectroscopy. Used to control the cell adhesion or cell growth. Used for: the development/analysis of pharmaceutical preparations; the diagnosis of diseases; the identification pathogens, mutated genes in humans/animal; and the analysis of micro-biological contamination in water, food, animal feed or soil sample. Used as electronic package in a biological computer (all claimed). ADVANTAGE - The support is fast, economic, very sensitive and reliably reproducible.