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Functionalization Strategies for Antibodies: Lessons Learned

 
: Schmidt, Christian; Geyer, Martin; Bohrisch, Jörg; Jentzen, Verena; Gorczyza, Alexander; Khalil, Karim; Volkert, Marina; Brown, Mark A.; Sel, Saadettin; Storsberg, Joachim

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Fulltext urn:nbn:de:0011-n-4534405 (517 KByte PDF)
MD5 Fingerprint: 28392e67d829b5ee7ed722a8229ec70c
Created on: 8.7.2017


American Journal of Immunology 13 (2017), No.2, pp.144-154
ISSN: 1553-619X (print)
ISSN: 1558-3775 (online)
Bundesministerium für Wirtschaft und Technologie BMWi
Zentrale Innovationsprogramm Mittelstand (ZIM); KF2302415AJ4
English
Journal Article, Electronic Publication
Fraunhofer IAP ()

Abstract
Precious little is known about useful functionalization strategies of antibodies that will not impair either reactivity or specificity of this valuable reagent. We used an experimental approach to demonstrate our own experience with published protocols. The conjugates obtained were then tested with regard to their performance against commercially available detection kits. Our results are then viewed in light of published precedence to highlight areas where future effort is needed to refine such versatile tools.

: http://publica.fraunhofer.de/documents/N-453440.html