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Chitindeacetylase und Verfahren zu seiner Herstellung

Nucleic acid encoding chitin deacetylase, useful for preparing chitosan for use in medicine, agriculture and foods, also related proteins and antibodies
 
: Zakaria, H.; Otto, B.; Schmalz, C.

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Frontpage ()

DE 2001-10111083 A: 20010308
DE 2001-10111083 A: 20010308
WO 2002-EP2585 A: 20020308
DE 10111083 B4: 20060622
C12N0009
C12N0015
German
Patent, Electronic Publication
Fraunhofer IGB ()

Abstract
Die vorliegende Erfindung betrifft Chitindeacetylasesequenzen und davon codierte Proteine, die fuer die Umsetzung von Biopolymeren zu Glucosamin geeignet sind.

 

WO 200270712 A UPAB: 20030129 NOVELTY - Nucleic acid (I) that encodes a protein (II) with chitin deacetylase activity is new. DETAILED DESCRIPTION - Nucleic acid (I) that encodes a protein (II) with chitin deacetylase activity is: (a) any of sequences (1)-(7), reproduced, of 636-1518 bp, or their fragments; (b) a sequence that encodes proteins (8)-(13), reproduced, of 211-356 amino acids; (c) the complement of (a) or (b); (d) a sequence derived from (a)-(c) by substitution, addition, inversion and/or deletion of one or more nucleotides; or (e) a sequence that, e.g. because of the degeneracy of the genetic code, hybridizes to (a)-(d) or their fragments. INDEPENDENT CLAIMS are also included for: (1) vector that contains (I); (2) host cell containing (I) or the vector of (1); (3) protein (II) encoded by (I) or produced by cells of (2); (4) antibody (Ab) that reacts with (II); (5) recombinant production of (II); and (6) production of chitosan from chitin by treatment with (II) or the cells of (2). USE - (II), Or cells that express it, are used to convert chitin to chitosan, for use in pharmaceuticals, agriculture and foods. Antibodies raised against (II) are useful for affinity purification and/or detection of (II). ADVANTAGE - (I) Makes possible industrial scale, inexpensive, non-polluting and efficient production of chitosan.

: http://publica.fraunhofer.de/documents/N-44182.html