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Anti-plasmodium parasite antibodies

Anti-Plasmodium-Parasiten-Antikörper
 
: Fischer, Rainer; Reimann, Andreas; Maskus, Dominika Jacqueline; Fendel, Rolf; Klockenbring, Torsten

EP 3081575 A1: 20150412
English
Patent
Fraunhofer IME ()

Abstract
The technology provided herein relates to novel human antibodies against Plasmodium parasites, in particular against the malaria parasite Plasmodium falciparum. The present disclosure pertains to antibodies against apical membrane antigen 1 (AMA-1). These antibodies have high affinity e.g. to Plasmodium falciparum schizonts and merozoites, inhibit the reinvasion of merozoites into erythrocytes and thereby neutralize parasitic multiplication.

: http://publica.fraunhofer.de/documents/N-426284.html