Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.

The role of epigenetics in host-parasite coevolution: Lessons from the model host insects Galleria mellonella and Tribolium castaneum

: Vilcinskas, A.


Zoology 119 (2016), No.4, pp.273-280
ISSN: 0944-2006
ISSN: 1873-2720
Journal Article
Fraunhofer IME ()

Recent studies addressing experimental host-parasite coevolution and transgenerational immune priming in insects provide evidence for heritable shifts in host resistance or parasite virulence. These rapid reciprocal adaptations may thus be transferred to offspring generations by either genetic changes or mechanisms that do not involve changes in the germline DNA sequence. Epigenetic inheritance refers to changes in gene expression that are heritable across generations and mediated by epigenetic modifications passed from parents to offspring. Highlighting the role of epigenetics in host-parasite coevolution, this review discusses the involvement of DNA methylation, histone acetylation/deacetylation and microRNAs in the interactions between bacterial or fungal parasites and model host insects such as the greater wax moth Galleria mellonella and the red flour beetle Tribolium castaneum.