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Indoor air guide values for glycol ethers and glycol esters - A category approach

: Mangelsdorf, Inge; Nordqvist Kleppe, Sara; Heinzow, Birger; Sagunski, Helmut


International journal of hygiene and environmental health 219 (2016), No.4-5, pp.419-436
ISSN: 1438-4639
Journal Article
Fraunhofer ITEM ()
glycol ethers; glycol esters; category approach; TTC; toxicological databases; guide value; indoor air

The German Committee on Indoor Guide Values issues indoor air guide values to protect public health. For health evaluation of glycol ethers and glycol esters in air, the entire group of substances with data for 47 chemicals was analyzed in order to gain a consistent assessment. For some glycol ethers reproductive and hematological effects are of central interest, whereas for others effects on liver and kidneys are crucial. Moreover, some glycol ethers have also been shown to cause irritation of the respiratory tract. For 14 chemicals, suitable inhalation studies were available for deriving specific guide values, or analogies to closely related substances could be drawn. For these chemicals individual indoor air guide values were derived, the respective guide value I ranging from 0.02 to 2 mg/m3.