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Use of BLT2 agonists as analgesisc

 
: Scholich, Klaus; Zinn, Sebastian; Geisslinger, Gerd; Bruin, Natasja de

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Frontpage ()

EP 3017813 A1: 20141104
English
Patent, Electronic Publication
Fraunhofer IME ()

Abstract
The present invention pertains to novel analgesics useful for treating pain. BLT2 agonists were found to desensitize TRPV1 mediated signalling in sensory neurons. Thus the invention provides BLT2 agonists as novel pain therapeutics. Additional aspects of the invention pertain to combinations of BLT2 agonists with BLT1 antagonists for treating pain in subjects. Pharmaceutical compositions and kits comprising the new analgesics of the invention are furthermore provided.

: http://publica.fraunhofer.de/documents/N-404992.html