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Metabolites from nematophagous fungi and nematicidal natural products from fungi as alternatives for biological control. Pt.II: Metabolites from nematophagous basidiomycetes and non-nematophagous fungi

: Degenkolb, T.; Vilcinskas, A.

Fulltext (PDF; )

Applied microbiology and biotechnology 100 (2016), No.9, pp.3813-3824
ISSN: 0171-1741
ISSN: 0175-7598
ISSN: 1432-0614
Journal Article, Electronic Publication
Fraunhofer IME ()

In this second section of a two-part mini-review article, we introduce 101 further nematicidal and non-nematicidal secondary metabolites biosynthesized by nematophagous basidiomycetes or non-nematophagous ascomycetes and basidiomycetes. Several of these compounds have promising nematicidal activity and deserve further and more detailed analysis. Thermolides A and B, omphalotins, ophiobolins, bursaphelocides A and B, illinitone A, pseudohalonectrins A and B, dichomitin B, and caryopsomycins A-C are excellent candidates or lead compounds for the development of biocontrol strategies for phytopathogenic nematodes. Paraherquamides, clonostachydiol, and nafuredins offer promising leads for the development of formulations against the intestinal nematodes of ruminants.