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Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments

: Lipka, Jens; Semmler-Behnke, Manuela; Wenk, Alexander; Burkhardt, Jana; Aigner, Achim; Kreyling, Wolfgang

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Data in Brief 7 (2016), pp.1175-1178
ISSN: 2352-3409
Journal Article, Electronic Publication
Fraunhofer IZI ()
biokinetic data; lung; PEI

Biokinetics data of lung-administered PEI F25-LMW/siRNA polyplexes within different lung compartments are presented. Thereby, at three different timepoints (1 h, 3 h, 8 h), the data was determined by calculations to the 32P-radioactivity in the whole mouse body. Additionally, data was optimized to the available PEI F25-LMW/siRNA polyplexes in the target organ and therefore normalized to the sum of all lung compartments. Methods, other biokinetics data and the discussion of the results are published in "Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice"