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Oxygen and ammonia plasma treatment of poly(3-hydroxybutyrate) films for controlled surface zeta potential and improved cell compatibility

: Syromotina, D.S.; Surmenev, R.A.; Surmeneva, M.A.; Boyandin, A.N.; Epple, M.; Ulbricht, M.; Oehr, C.; Volova, T.G.


Materials letters 163 (2016), pp.277-280
ISSN: 0167-577X
Journal Article
Fraunhofer IGB ()

The oxygen and ammonia radio-frequency (RF) plasma treatment of poly(3-hydroxybutyrate) P3HB films was performed. We revealed significant changes in the topography, a decrease in the surface zeta potential from -63 to -75 mV after the oxygen-plasma treatment and an increase after ammonia plasma treatment from -63 to -45 mV at a pH of 7.4. Investigations into the NIH 3T3 fibroblast adhesion and growth demonstrated the best cell vitality and a higher cell number for the ammonia plasma treatment at 150W.