Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.

Isothermal titration calorimetry of molecularly imprinted polymer nanospheres

: Weber, A.; Dettling, M.; Brunner, H.; Tovar, G.E.M.


Macromolecular rapid communications 23 (2002), 14, pp.824-828
ISSN: 1022-1336
ISSN: 1521-3927
Journal Article
Fraunhofer IGB ()

Ultrasensitive, isothermal titration calorimetry was used to generate thermodynamic data to assess the binding properties of molecularly imprinted polymer microgels. Microgels were imprinted using L-boc-phenylalanine anilide (L-BFA) and then utilized in binding experiments with a variety of probe molecules, structurally closely related to the template molecule. Significant differences were observed between the binding enthalpy of the original template L-BFA and those of D-BFA, L-boc-phenylalanine, L-boc-tryptophane, and L-boc-tyrosine.