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Proton-Transfer-Reaction Time-of-Flight Mass Spectrometry (PTR-TOFMS) for Aroma Compound Detection in Real-Time: Technology, Developments, and Applications

: Beauchamp, J.; Herbig, J.


Guthrie, Brian (Ed.); Beauchamp, Jonathan (Ed.); Buettner, Andrea (Ed.); Lavine, Barry K. (Ed.) ; American Chemical Society -ACS-, Washington/D.C.:
The Chemical Sensory Informatics of Food: Measurement, Analysis, Integration
Washington, DC: ACS, 2015 (ACS Symposium Series 1191)
ISBN: 9780841230699
ISBN: 9780841230705
DOI: 10.1021/bk-2015-1191
Book Article
Fraunhofer IVV ()

Proton transfer reaction-mass spectrometry, PTR-MS, is an established tool in flavour research for the real-time detection of volatile aroma compounds in both in vitro and in vivo applications. The latter development of a PTR-MS system coupled to a time-of-flight mass spectrometer, PTR-TOFMS, provides unprecedented time and mass resolution in the real-time analysis of odorants. This chapter reviews the technology and reports on latest developments of PTR-TOFMS, including a fast gas-chromatographic pre-separation stage, autosampling capabilities and sensitivity improvements. Selected food-flavour applications are also reviewed and discussed.