Detection, binding, signalling: Functional molecules for biosensors

Abstract
Diagnostics are essential for detecting infectious agents and the assessment of a disease. In the joint research project The Lab in a Hankie Impulse Centre for Integrated Bioanalysis the complete integration of all necessary processing steps was intended. Work has been done on a new class of sensor-actor molecules integrating detection and signalling and being applicable to complex matrices. Defining binding parts, assembly on a polymer scaffold, enabling signal generation and amplification were central goals of this project.