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Interfacing regenerating peripheral nerves with a micromachined polyimide sieve electrode

: Stieglitz, T.; Navarro, X.; Blau, C.; Meyer, J.-U.


Boom, H. ; IEEE Engineering in Medicine and Biology Society -EMBS-:
Engineering in medicine & biology. 18th International Conference 1996. Vol.1 : 31 October - 3 November 1996, Amsterdam
Piscataway, NJ: IEEE, 1996
ISBN: 0-7803-3811-1
IEEE Engineering in Medicine and Biology Society (Conference) <18, 1996, Amsterdam>
Conference Paper
Fraunhofer IBMT ()

A design of a flexible, light-weighted sieve electrode with integrated cables for interfacing regenerating nerves has been developed using micromachining technologies. The authors used polyimide as substrate and insulation layers and platinum as electrode metallization. The materials showed no cytotoxic effects in biocompatibility testing. In first chronic experiments on the sciatic nerve of rats, the authors received good regeneration, a functional reinervation, and no mechanical traumatization of the nerve caused by the microsystem due to the flexible materials.