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Interaction of technically relevant nanoparticles with cells

: Gelinsky, M.; Springer, A.; Hanke, T.; Iwe, M.; Bastian, S.; Ikonomidou, H.; Kühnel, D.; Busch, W.; Scholz, S.; Schirmer, K.; Meissner, T.; Richter, V.; Potthoff, A.; Pompe, W.

8th World Biomaterials Congress 2008. Vol.1 : Amsterdam, the Netherlands, 28 May - 1 June 2008
Red Hook, NY: Curran, 2008
ISBN: 978-1-61567-080-2
World Biomaterials Congress (WBC) <8, 2008, Amsterdam>
Conference Paper
Fraunhofer IKTS ()

Engineered NP may be cytotoxic which was found not only to be due to the dissolution of toxic components, but might be a defined particle induced effect, not well understood until now. WC NP were found to be not toxic, whereas WC-Co NP were demonstrated to be highly cytotoxic for several cell types investigated in this study. Both are able to pass the outer cell membrane but can not get into the nuclei.