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Noninvasive quality control of cryopreserved samples

: Dörr, D.; Stracke, F.; Zimmermann, H.


Biopreservation and Biobanking 10 (2012), No.6, pp.529-531
ISSN: 1947-5535
ISSN: 1947-5543
Journal Article
Fraunhofer IBMT ()

We present a novel noninvasive technology for quality control in biobanking. We implemented a contactless optical in situ method with a remote detection unit. The method detects physical and chemical changes by emission spectroscopy. In the present study, ice formation in a vitrified sample is revealed by Raman scattering. The technology allows us to monitor sample quality during cold storage and to assess the sample state after preservation, storage, or transport without the need for thawing.