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Combination of channel- and droplet- based microfluidics for complex PoC-Devices

 
: Georgi, Leopold; Jung, Erik; Bauer, Jörg; Braun, Tanja; Schuldt, Victoria; Metwally, Khaled; Robert, Laurent; Khan-Malek, Chantal

:

Kück, H. ; 4M Association:
4M 2011, 8th International Conference on Multi-Material Micro Manufacture. Proceedings : 8 - 10 November 2011, Stuttgart, Germany
Singapore: Research Publishing, 2011
ISBN: 978-981-07-0319-6 (Buch)
ISBN: 978-981-07-0320-2 (CD-ROM)
pp.183-186
International Conference on Multi-Material Micro Manufacture (4M) <8, 2011, Stuttgart>
English
Conference Paper
Fraunhofer IZM ()

Abstract
This paper presents a microfluidic device addressing the field of ambulant diagnostics. The basis of the device is a hybrid system combining the advantages of conventional channel-based fluidics with those of digitally controlled droplet-based fluidics. This hybrid concept uses a micro-channel based delivery partition with a disposable reaction partition predicated on electrowetting-on-dielectric. It promises to realize a low cost approach for a Point-of-Care system with easy deployability. Implementation was done by roll embossing for the microchannels and direct structuring of the electrode elements for the EWOD substrate. The latter was laminated with a PTFE-film or coated with a nanoparticle loaded lacquer for hydrophobization. A variety of reagents were handled using a two- phase containment on the EWOD substrate, overcoming the issues associated with low surface energy fluids.

: http://publica.fraunhofer.de/documents/N-234327.html