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Solid-phase microextraction for bioconcentration studies referred to OECD TG 305

Running head: SPME for fish bioconcentration studies
 
: Düring, Rolf-Alexander; Böhm, Leonard; Schlechtriem, Christian

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Fulltext (PDF; )

Environmental Sciences Europe : ESEU 24 (2012), Art. 4, 5 pp.
ISSN: 2190-4715
ISSN: 2190-4707
English
Journal Article, Electronic Publication
Fraunhofer IME ()
particulate and dissolved organic matter; bioconcentration factor; bioavailability; hydrophobic organic chemicals; registration and authorization of chemicals

Abstract
An important aim of the European Community Regulation on chemicals and their safe use is the identification of (very) persistent, (very) bioaccumulative, and toxic substances. In other regulatory chemical safety assessments (pharmaceuticals, biocides, pesticides), the identification of such (very) persistent, (very) bioaccumulative, and toxic substances is of increasing importance. Solidphase microextraction is especially capable of extracting total water concentrations as well as the freely dissolved fraction of analytes in the water phase, which is available for bioconcentration in fish. However, although already well established in environmental analyses to determine and quantify analytes mainly in aqueous matrices, solid-phase microextraction is still a rather unusual method in regulatory ecotoxicological research. Here, the potential benefits and drawbacks of solidphase microextraction are discussed as an analytical routine approach for aquatic bioconcentration studies according to OECD TG 305, with a special focus on the testing of hydrophobic organic compounds characterized by log KOW > 5.

: http://publica.fraunhofer.de/documents/N-217183.html