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Microfluidics meets soft layer-by-layer films: Selective cell growth in 3D polymer architectures

: Madaboosi, N.; Uhlig, K.; Schmidt, S.; Jäger, M.S.; Möhwald, H.; Duschl, C.; Volodkin, D.V.


LAB on a chip 12 (2012), No.8, pp.1434-1436
ISSN: 1473-0197
ISSN: 1473-0189
Journal Article
Fraunhofer IBMT ()

We present here the micropatterns of layer-by-layer (LbL) assembled soft films generated using microfluidic platform that can be exploited for selective cell growth. Using this method, the issue of cell adhesion and spreading on soft LbL-derived films, and simultaneous utilisation of such unmodified soft films to exploit their reservoir properties are addressed. This also paves the way for extending the culture of cells to soft films and other demanding applications like triggered release of biomolecules.