"Sensorfilter": Intelligent micro-filter in foil technology for applications in proces culture and cell culture

Abstract
A novel micro filter system (sensor filter) enables standalone detection of its own loading status as well as monitoring the filtrate for the first time. This sensor filter consists of two micro-perforated sensor-foils containing interdigital capacitors (IDC) and a filter membrane placed in between. The capacitive detection of the filtrate (cells or particles) is possible via the alteration of the permittivity of the fluid upstream the filter at the upper IDC. The lower IDC downstream the filter serves to compensate temperature and / or conductivity variations of the fluid itself.