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Rapid fabrication of biocompatible hydrogels microdevices using laser interference lithography

: Lasagni, A.; Yuan, D.; Shao, P.; Das, S.


Rodríguez-Vázquez, A.B. ; Society of Photo-Optical Instrumentation Engineers -SPIE-, Europe, Cardiff:
Bioengineered and bioinspired systems IV. Proceedings : 4 May 2009, Dresden, Germany
Bellingham, WA: SPIE, 2009 (SPIE Proceedings 7365)
ISBN: 978-0-8194-7639-5
ISBN: 0-8194-7639-0
Art. 73650I
Conference "Bioengineered and Bioinspired Systems" <4, 2009, Dresden>
Conference Paper
Fraunhofer IWS ()

We report on fabrication of periodic arrays of polyethylene glycol diacrylate (PEG-DA), a biocompatible hydrogel, useful in biomedical applications. The structures were produced by means of multi beam laser interference lithography with both nanosecond (266 and 355 nm of wavelengths with pulses lasting 10 ns) and femtosecond pulsed lasers (800 nm of wavelength and 90 fs laser pulses). Configurations involving two, four and five laser beams were utilized obtaining a wide variety of patterns with different feature sizes in the micrometer scale. Through this technique, we demonstrated the ability to fabricate high feature density patterns over large areas without the use of templates or masks. In addition, resolution and geometrical characteristic of the periodic arrays are discussed as function of pulse duration and laser processing parameters. The photopolymerization nature of the process was also investigated. ©2009 SPIE.