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Microfluidic manifolds with high dynamic range in structural dimensions replicated in thermoplastic materials

: Becker, H.; Beckert, E.; Gärtner, C.

Murthy, S.K. ; Materials Research Society -MRS-:
Materials and strategies for lab-on-a-chip - biological analysis, cell-material interfaces and fluidic assembly of nanostructures : Symposium held April 14 - 17, San Francisco, California, U.S.A.; Symposium OO; held at the 2009 MRS spring meeting
Warrendale, Pa.: MRS, 2009 (Materials Research Society Symposium Proceedings 1191)
ISBN: 978-1-605-11164-3
ISBN: 1-605-11164-3
ISSN: 0272-9172
Symposium OO "Materials and Strategies for Lab-on-a-Chip - Biological Analysis, Cell-Material Interfaces and Fluidic Assembly of Nanostructures" <2009, San Francisco/Calif.>
Materials Research Society (Spring Meeting) <2009, San Francisco/Calif.>
Conference Paper
Fraunhofer IOF ()

In this paper, we present the manufacturing process of a polymer microfluidic device which is currently being used to investigate wetting properties of nanostructured microchannels replicated in hydrophobic thermoplastic materials like cyclo-olefin co-polymer (COC), polypropylene (PP) or polymethylmetacrylate (PMMA). These devices feature large structural dynamics (feature sizes between 200 m and 200 nm). The mold insert necessary was fabricated using a combination of precision machining with single-point diamond turning (SPDT).