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First chronic results from a flexible sieve electrode to interface nerves without the need for guidance channels

 
: Stieglitz, T.; Rosahl, S.K.; Poessnecker, J.; Haastert, K.; Brinker, T.; Meyer, J.-U.

:

Clark, J.W.:
Engineering in Medicine and Biology, 2002. Vol.3 : Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference 2002
Piscataway: IEEE Service Center, 2002
ISBN: 0-7803-7612-9
ISSN: 0589-1019
pp.2056-2057
Annual international conference of the Engineering in Medicine and Biology Society (EMBS) <24, 2002, Houston>
Annual fall meeting of the Biomedical Engineering Society (BMES) <2002, Houston>
English
Conference Paper
Fraunhofer IBMT ()

Abstract
Nerves has been previously interfaced with micro-machined sieve electrodes for recording and stimulation purposes. In most cases, so-called guidance channels have to be assembled on the sieve to adjust and fix the nerve in the vicinity of the microstructure. In this paper, a new approach of a flexible, polyimide-based sieve electrode is presented. Monolithically integrated fixation flaps offer the opportunity to directly fix the sieve implant on a transected nerve without the need for a guidance channel. The sieve has been fabricated with a thickness of 10 m and chronically implanted between the transected ends of the sciatic nerve of rats. First electrophysiological experiments proved a functional reinnervation and a selective and graded stimulation over ring electrodes around single holes of 40 m diameter in the sieve area.

: http://publica.fraunhofer.de/documents/N-170256.html