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Self-Assembled Microarrays of Attoliter Molecular Vessels

: Stamou, D.; Duschl, C.; Delamarche, E.; Vogel, H.


Angewandte Chemie. International edition 42 (2003), No.45, pp.5580-5583
ISSN: 1433-7851
ISSN: 0044-8249
ISSN: 0570-0833
ISSN: 1521-3773
Journal Article
Fraunhofer IBMT ()

High-density microarrays of attoliter volume elements can be created (see figure) within minutes in a parallel and effortless manner by using self-assembly of nanometer-size components based on biological recognition. These ultrasmall volumes allow localization of single molecules, screening for (bio)chemical properties, and assessing the performance of confined chemical reactions.