Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.

Oriented immobilization of single DNA molecules as a nanostructuring tool

: Bier, F.F.; Gajovic-Eichelmann, N.; Holzel, R.

Fritzsche, W. ; American Institute of Physics -AIP-, New York:
DNA-based molecular construction : International Workshop on DNA-Based Molecular Construction, Jena, Germany, 23 - 25 May 2002
Woodbury, N.Y.: AIP, 2002 (AIP Conference Proceedings 640)
ISBN: 0-7354-0095-4
International Workshop on DNA Based Molecular Construction <2002, Jena>
Conference Paper
Fraunhofer IBMT ()
oriented immobilization; single DNA molecule; AC field; end anchoring; nanostructuring tool; DNA stretching; oligo-tag method; immobilization technique; biophysical technique; molecular fixing at each end

To facilitate the directed positioning of molecules on a surface the use of nucleic acids is proposed. For nanostructuring with DNA the deposition of each molecule has to be directed. Two steps are necessary: First, the DNA has to be stretched and second the lengthened molecule has to be fixed at each end in a specific manner. For stretching DNA of several micrometers length AC fields are applied, and for anchoring the ends in a specific manner the oligo-tag method is applied using different immobilization techniques.