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ACE-gene polymorphism is associated with the development of allograft vascular disease in heart transplant recipients

: Pethig, K.; Heublein, B.; Hoffmann, A.; Borlak, J.; Wahlers, T.; Haverich, H.


The journal of heart and lung transplantation 19 (2000), No.12, pp.1175-1182
ISSN: 1053-2498
Journal Article
Fraunhofer ITA ( ITEM) ()
genetic polymorphism; Transplantation of organs; complication; heart

Cardiac allograft vascular disease is (CAVD) the most important cause of death following heart transplantation (HTX). Although in the past, researchers focused predominantly on mechanisms of endothelial injury, the possible role of recipient-related and genetically determined factors has not been studied in detail.