Fraunhofer-Gesellschaft

Publica

Hier finden Sie wissenschaftliche Publikationen aus den Fraunhofer-Instituten.
2019The rat bone marrow micronucleus test: Statistical considerations on historical negative control data
Igl, Bernd-Wolfgang; Bitsch, Annette; Bringezu, Frank; Chang, Steffi; Dammann, Martina; Frötschl, Roland; Harm, Volker; Kellner, Rupert; Krzykalla, Volker; Lott, Jasmin; Nern, Marlies; Pfuhler, Stefan; Queisser, Nina; Schulz, Markus; Sutter, Andreas; Vaas, Lea; Vonk, Richardus; Zellner, Dietmar; Ziemann, Christina
Zeitschriftenaufsatz
2018Genotoxic and mutagenic potential of camphorquinone in L5178/TK(+/-) mouse lymphoma cells
Volk, Joachim; Ziemann, Christina; Leyhausen, Gabriele; Geurtsen, Werner
Zeitschriftenaufsatz
2018ICONS - Integrated testing strategy for mechanistically assessing the respiratory toxicity of functionalized MWCNTs - Comparative in vitro investigations
Ziemann, Christina; Reamon-Buettner, Stella Marie; Lison, Dominique; Bonner, J.C.; Brûle, Sybille van den; Simon, S.; Creutzenberg, Otto H.
Abstract
2018Platox in vitro and in vivo investigations (28-day inhalation) to generate valid toxicity data for risk assessment of carbon-based nanoplatelets
Creutzenberg, Otto H.; Ziemann, Christina; Oliveira, H.; Farcal, L.; Burla, S.
Abstract
2018The PLATOX project: Combining in vitro and in vivo investigations to generate valid toxicity data for risk assessment of graphene nanoplatelets
Creutzenberg, Otto H.; Ziemann, Christina; Schaudien, Dirk; Oliveira, Helena; Farcal, Lucian
Abstract
2018Untersuchungen zum zytotoxischen, gentoxischen und pro-inflammatorischen Potential von Graphen-Nanoplättchen in Rattenalveolarmakrophagen
Gripp, Tatjana
: Noll, Thomas (1. Gutachter); Ziemann, Christina (2. Gutachter)
Master Thesis
2017Biological effects of carbon black nanoparticles are changed by surface coating with polycyclic aromatic hydrocarbons
Lindner, Karina; Ströbele, Michael; Schlick, Sandra; Webering, Sina; Jenckel, André; Kopf, Johannes; Danov, Olga; Sewald, Katherina; Buj, Christian; Creutzenberg, Otto; Tillmann, Thomas; Pohlmann, Gerhard; Ernst, Heinrich; Ziemann, Christina; Hüttmann, Gereon; Heine, Holger; Bockhorn, Henning; Hansen, Tanja; König, Peter
Zeitschriftenaufsatz
2017Organosilane-based coating of quartz species from the traditional ceramics industry: Evidence of hazard reduction using in vitro and in vivo tests
Ziemann, Christina; Escrig, Alberto; Bonvicini, Giuliana; Ibañez, Maria Jesus; Monfort, Eliseo; Salomoni, Arturo; Creutzenberg, Otto H.
Zeitschriftenaufsatz
2016FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity
Wiesner, Jochen; Ziemann, Christina; Hintz, Martin; Reichenberg, Armin; Ortmann, Regina; Schlitzer, Martin; Fuhst, Rainer; Timmesfeld, Nina; Vilcinskas, Andreas; Jomaa, Hassan
Zeitschriftenaufsatz
2015Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing
Guerard, M.; Baum, M.; Bitsch, Annette; Eisenbrand, G.; Elhajouji, A.; Epe, B.; Habermeyer, M.; Kaina, B.; Martus, H.J.; Pfuhler, S.; Schmitz, C.; Sutter, A.; Thomas, A.D.; Ziemann, Christina; Froetschl, R.
Zeitschriftenaufsatz
2015Influence of ELF-MF on the juvenile immune system of CD-1 mice
Müller, Meike; Ziemann, Christina; Tillmann, Thomas; Lewin, Geertje; Dasenbrock, Clemens
Abstract
2015Inhalation toxicity of carbon black depends on surface coating with polycyclic aromatic hydrocarbons
Hansen, Tanja; König, P.; Creutzenberg, Otto H.; Weinhold, K.; Schlick, S.; Tillmann, Thomas; Pohlmann, Gerhard; Kolling, Angelika; Ziemann, Christina; Kopf, Johannes; Ströbele, Michael; Bockhorn, H.; Danov, Olga; Sewald, Katherina; Müller, B.; Fehrenbach, Heinz
Abstract
2015New investigations into the genotoxicity of cobalt compounds and their impact on overall assessment of genotoxic risk
Kirkland, David; Brock, Tom; Haddouk, Hasnaà; Hargeaves, Victoria; Lloyd, Melvyn; Mc Garry, Sarah; Proudlock, Raymond; Sarlang, Séverine; Sewald, Katherina; Sire, Guillaume; Sokolowski, Andrea; Ziemann, Christina
Zeitschriftenaufsatz
2015The SILICOAT project
Ziemann, Christina; Rahmer, Hartmut; Escrig Vidal, A.; Bonvicini, Giuliana; Ibanez Garcia, M.J.; Monfort Gimeno, E.; Creutzenberg, Otto H.
Konferenzbeitrag, Zeitschriftenaufsatz
2015The Silicoat project: In vitro and in vivo toxicity screening of quartz varieties from ceramics industry and approaches for an effective quartz surface coating
Creutzenberg, Otto H.; Reamon-Buettner, Stella Marie; Tillmann, Thomas; Hansen, Tanja; Garcia, M.J.; Monfort, Eliseo; Bonvicini, Giuliana; Escrig, Alberto; Ziemann, Christina
Abstract
2014CEFIC-LRI N1 project: Genotoxicity of a synthetic amorphous silica (SAS) in rats
Knebel, Jan; Ziemann, Christina; Creutzenberg, Otto H.
Abstract
2014Lack of marked cyto- and genotoxicity of cristobalite in devitrified (heated) alkaline earth silicate wools in short-term assays with cultured primary rat alveolar macrophages
Ziemann, Christina; Harrison, Paul T.C.; Bellmann, Bernd; Brown, Robert C.; Zoitos, Bruce K.; Class, Philippe
Zeitschriftenaufsatz
2014Multiwalled carbon nanotubes (MWCNT) induce DNA damage and cellular senescence in human peritoneal mesothelial LP9 cells
Reamon-Büttner, Stella Marie; Bellmann, Bernd; Hackbarth, Anja; Leonhardt, Albrecht; Niehof, Monika; Ziemann, Christina
Zeitschriftenaufsatz, Konferenzbeitrag
2014Prostaglandin D2-supplemented "functional eicosanoid testing and typing" assay with peripheral blood leukocytes as a new tool in the diagnosis of systemic mast cell activation disease
Schäfer, Dirk; Dreßen, Peter; Brettner, Stefan; Rath, Norbert-Folke; Molderings, Gerhard J.; Jensen, Katrin; Ziemann, Christina
Zeitschriftenaufsatz
2014The SILICOAT project: In vitro and in vivo toxicity screening of quartz varieties from traditional ceramics industry and approaches for an effective quartz surface coating
Ziemann, Christina; Reamon-Buettner, Stella Marie; Tillmann, Thomas; Hansen, Tanja; Ibañez, Maria Jesus; Monfort, Eliseo; Bonvicini, Giuliana; Escrig, Alberto; Creutzenberg, Otto H.
Zeitschriftenaufsatz, Konferenzbeitrag
2013Evaluation of immunohistochemical markers to detect the genotoxic mode of action of fine and ultrafine dusts in rat lungs
Rittinghausen, Susanne; Bellmann, Bernd; Creutzenberg, Otto; Ernst, Heinrich; Kolling, Angelika; Mangelsdorf, Inge; Kellner, Rupert; Beneke, Sascha; Ziemann, Christina
Zeitschriftenaufsatz
2013Evaluation of the gentoxic potential of different radiofrequency electromagnetic fields in MRC-5 cells and B6C3F1 mice
Ziemann, Christina; Tillmann, Thomas; Oertel, Antje; Brockmeyer, Heidrun; Murbach, M.; Capstick, M.; Kuster, N.; Dasenbrock, Clemens
Zeitschriftenaufsatz, Konferenzbeitrag
2013Human peritoneal mesothelial LP9 cells as a model system to determine the toxic and genotoxic potential of multiwalled carbon nanotubes (MWCNTs)
Reamon-Büttner, Stella Marie; Hackbarth, Anja; Voepel, Ines Rebeca; Brockmeyer, Heidrun; Bellmann, Bernd; Ziemann, Christina
Zeitschriftenaufsatz, Konferenzbeitrag
2013Human pleural mesothelial MeT-5A cells are a limited in vitro model for detection of potential asbestos-like genotoxic effects of multiwall carbon nanotubes
Ziemann, Christina; Reamon-Büttner, Stella Marie; Hackbarth, Anja; Brockmeyer, Heidrun; Rahmer, Hartmut; Bellmann, Bernd
Zeitschriftenaufsatz, Konferenzbeitrag
2013Multiwall carbon nanotubes exhibit a cytotoxic but not directly DNA-damaging potential in human LP9/TERT-1 peritoneal mesothelial cells
Hackbarth, Anja; Ziemann, Christina; Albrecht, L.; Steinberg, Pablo; Bellmann, Bernd
Zeitschriftenaufsatz, Konferenzbeitrag
2013No direct genotoxic potential of different radiofrequency electromagnetic fields in MRC-5 cells and B6C3F1 mice
Dasenbrock, Clemens; Tillmann, Thomas; Oertel, Antje; Brockmeyer, Heidrun; Murbach, M.; Capstick, M.; Kuster, N.; Ziemann, Christina
Zeitschriftenaufsatz, Konferenzbeitrag
2013Toxic effects of multiwall carbon nanotubes (MWCNT) in vivo and in vitro
Hackbarth, Anja; Schaudien, Dirk; Bellmann, Bernd; Ernst, Heinrich; Ziemann, Christina; Leonhardt, A.; Heinrich, Uwe; Rittinghausen, Susanne
Zeitschriftenaufsatz, Konferenzbeitrag
2013Toxic effects of MWCNT in vivo and in vitro
Schlichting, Anja; Ziemann, Christina; Leonhardt, A.; Rittinghausen, Susanne; Schaudien, Dirk; Bellmann, Bernd
Zeitschriftenaufsatz, Konferenzbeitrag
2012Human pleural mesothelial MeT-5A cells are a limited in vitro model system in determining potential asbestos-like effects of multiwall carbon nanotubes
Ziemann, Christina; Reamon-Büttner, Stella-Marie; Schlichting, Anja; Brockmeyer, Heidrun; Rahmer, Hartmut; Bellmann, Bernd
Zeitschriftenaufsatz, Konferenzbeitrag
2012International round-robin study on the Ames fluctuation test
Reifferscheid, Georg; Maes, Hanna; Allner, Bernhard; Badurova, Jana; Belkin, Shimshon; Bluhm, Kerstin; Brauer, Frank; Bressling, Jana; Domeneghetti, Stefania; Elad, Tal; Flückiger-Isler, Sini; Grummt, Hans-Juergen; Gürtler, Rainer; Hecht, Adiel; Heringa, Minne; Hollert, Henner; Huber, Stefanie; Kramer, Maike; Ratte, Toni; Sauerborn-Klobucar, Roberta; Magdeburg, Axel; Sokolowski, Andrea; Soldan, Premysl; Smital, Tvrtko; Stalter, Daniel; Venier, Paola; Ziemann, Christina; Zipperle, Jürgen; Buchinger, Sebastian
Zeitschriftenaufsatz
2012Subacute and subchronic inhalation toxicity and dermal absorption of the nanoscaled zinc oxide Z-COTE HP1 in the rat
Creutzenberg, Otto H.; Ziemann, Christina; Hansen, Tanja; Ernst, Heinrich; Schaudien, Dirk; Schuchardt, Sven; Wiench, Karin; Bellmann, Bernd
Zeitschriftenaufsatz
2012Suspension of MWCNT for toxicological in vivo and in vitro studies
Heinrich, Uwe; Schlichting, Anja; Ziemann, Christina; Seyock, S.; Haase, D.; Leonhardt, A.; Bellmann, Bernd
Zeitschriftenaufsatz
2012Zinc oxide-nanosize does not change the toxicological profile
Wiench, Karin; Schulte, Sabine; Champ, Simon; Ma-Hock, Lan; Schneider, S.; Creutzenberg, Otto; Bellmann, Bernd; Ziemann, Christina; Monteiro-Riviere, Nancy; Revenzwaay, Bernnard; Landsiegel, Robert
Zeitschriftenaufsatz
2011Discrepancy between high clastogenic activity of trans-beta-nitrostyrene in vitro and lack in carcinogenicity might be related to inactivating metabolism and its high reactivity towards thiol groups
Ziemann, Christina; Apitius, Florian; Elend, Manfred; Baumgartner, S.; Volk, J.; Ritter, Detlef; Steinfelder, H.J.; Schuchardt, Sven
Konferenzbeitrag, Zeitschriftenaufsatz
2011Nitrostyrolderivate als potentielle neue Zytostatika in der Therapie von Leukämien?
Baumgartner, S.
: Ziemann, Christina (Betreuer); Reinhardt, Dirk (Betreuer)
Dissertation